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Facts
About Atypical Pneumonia - Severe Acute Respiratory Syndrome (SARS)
SARS Raises its Head Once Again in Singapore.
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WHO July 14, 2003:
As of today WHO no longer publishes a daily table
of the cumulative number of reported probable cases of SARS.
WHO September 2, 2003:
The recent global outbreak of SARS has heightened
concern about the occurrence of respiratory diseases having symptoms similar to
those seen in SARS. Although the global outbreak of SARS has been contained
throughout the summer, considerable uncertainty surrounds the question of
whether SARS might recur, perhaps according to a seasonal pattern. Several
respiratory illnesses occur much less frequently when temperature and humidity
are high and then return when the weather turns cooler.
Currently, SARS has no vaccine, no effective treatment, and no reliable point-of
care diagnostic test.
Hong Kong September 9, 2003: East Asian
countries are on full alert after Singapore health authorities confirmed that a
local patient had contracted SARS. Hong Kong authorities have stepped up checks
at the airport and sent letters to all doctors to be on alert. It has also made
an agreement with mainland authorities to exchange information on infectious
diseases. Higher surveillance once again. At Hong Kong's international airport,
health checks are being tightened, especially on travelers from Singapore. |
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Today's Analysis of Severe Acute Respiratory Syndrome
(SARS) in Hong Kong |
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This
illness can be severe and, due to global travel, has spread to several
countries in a relatively short period of time. However,
SARS is not highly contagious when sensible protective measures are used,
and the percentage of cases that have been fatal is low.
SARS
appears to be less infectious than influenza. The incubation period is
short, estimated to range from 2-14 days, with 3-5 days being more common.
However, the speed of international travel creates a risk that cases can
rapidly spread around the world.
Observation
of the figures I have been collecting since March 17 indicate that the
death rate in Hong Kong of SARS patients has increased from 1.05% to
16.81%. Most of the deaths occurred in individuals who have a
history of chronic diseases, or were patients who sought treatment at a
relatively late stage of infection. WHO
Update: The
SARS virus is a new coronavirus unlike any other known human or animal
virus in the Coronavirus family. Because the virus is new, much about its behavior
is poorly understood. Key questions, which are undergoing intense study,
include stages in the course of infection when virus shedding may be
highest, and the various concentrations of virus in different body fluids.
Scientists are also working to determine the amount of time the virus can
survive in the environment on both dry surfaces and in suspension,
including in faecal matter. Experience
has shown that when SARS cases are promptly detected, isolated, and
managed according to strict procedures of infection control, further
spread to hospital staff and family members either does not occur at all
or results in a very small number of secondary infections. Information
emerging from outbreaks in Hong Kong and Canada is raising some important
new questions about SARS. In Hong Kong, a large and sudden cluster of
almost simultaneous cases (321) seen in residents of the Amoy Gardens
housing estate has raised the possibility of transmission from an
environmental source. Around 66% of Amoy Gardens patients present with
diarrhoea as a symptom, compared with 2% to 7% of cases in other
outbreaks. Some deaths are now occurring in younger, previously healthy
persons as well as in the elderly and persons with underlying disease. Speculation
centres on whether these cases represent infection with high virus loads,
as might occur following exposure to a concentrated environmental source,
or whether the virus may have mutated into a more virulent form. Viruses
in the Coronavirus family are known to mutate frequently. Lancet
Study May 6: The
first major study of SARS trends estimates that about 20 percent of the
people hospitalized with the disease in Hong Kong are dying from it, and
that more than half of those over 60 die. The average age of the SARS
patients in the study _ those hospitalized in Hong Kong _ is 50, and
disease experts generally agree that the virus is much more deadly in
people over 60. The death rate could be as high as 55 percent in people
over the age of 60. |
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Distribution of HK SARS
Patients by Age Group and Gender |
Distribution of onset date
and residential district of about 1,330 patients is shown in the chart
below. It can be seen that the onset date for most of the SARS cases in
Hong Kong was before 9 April. |
| Age group |
Male |
Female |
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| 0-14 |
3% |
3% |
| 15-24 |
4% |
7% |
| 25-34 |
10% |
16% |
| 35-44 |
9% |
12% |
| 45-54 |
6% |
9% |
| 55-64 |
4% |
4% |
| 65 or above |
9% |
5% |
| Total |
44% |
56% |
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Today's Analysis of Severe Acute Respiratory Syndrome
(SARS) Worldwide |
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What
are the Symptoms |
What Precautions
Should be Taken |
When in Public Places |
- high fever (> 38° Celsius, 100.4°
F)
- dry cough
- shortness of breath or breathing
difficulties
- changes in chest X-rays indicative of
pneumonia also occur
- SARS may be associated with other
symptoms, including headache, muscular stiffness, loss of appetite,
malaise, confusion, rash and diarrhea
Remember this is
a new virus that has not yet been identified in terms of its evolution and
behavior, and it is not yet definite
how it is transmitted. It is
apparent that it is spread through air droplets from infected people, and
also from hand-contact or from inanimate objects. Airborne transmission
has not yet been completely ruled out. All
viruses are susceptible to natural ingredients, particularly vitamin C
which has an inhibiting effect on virus replication. Some
WHO Definitions SARS
Affected Area: As at May 2 WHO is now issuing daily lists of
countries having areas where local transmission has occurred within the
past 20 days. This new list replaces the previous list of affected areas.
See list below.
SARS
Suspect Case:
1. A person presenting after 1 November 2002 with history of high
fever (>38 °C) AND cough or breathing difficulty
AND one or more of the following exposures during the 10 days prior to
onset of symptoms:
- close contact with a person who is a suspect or probable case
of SARS;
- history of travel, to an area
with recent local transmission of SARS
-
residing in an area
with recent local transmission of SARS
2. A
person with an unexplained acute respiratory illness resulting in death
after 1 November 2002, but on whom no autopsy has been performed AND one
or more of the following exposures during to 10 days prior to onset of
symptoms:
- close contact, with a person who is a suspect or probable
case of SARS;
- history of travel, to an area
with recent local transmission of SARS
-
residing in an area
with recent local transmission of SARS
SARS
Probable Case:
1. A
suspect case with radiographic evidence of infiltrates consistent with
pneumonia or respiratory distress syndrome (RDS) on chest X-ray (CXR).
2.
A suspect case of SARS that is positive for SARS coronavirus by one or
more assays. See Use of
laboratory methods for SARS diagnosis.
3. A suspect case with autopsy findings consistent with the
pathology of RDS without an identifiable cause.
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- maintain good personal hygiene for
the protection of yourself and others around you
- cover your nose and mouth when
coughing or sneezing
- keep your hands clean and wash them
frequently with liquid soap
- develop a habit of NOT touching your
face (eyes, nose, mouth, ears) with your hands - if you must touch
your face, wash hands first
- in public wear a surgical face mask;
don't touch the outside of it (wash hands if you do!); and change it
often
- keep a fair distance from people who
are ill and are sneezing and coughing openly. The virus is spread
through air droplets and you can pick up the virus through inhalation
- maintain good indoor ventilation at
home
- keep home environment clean and pay
special attention to cleaning the toilets: before flushing, lower the
toilet lid to prevent contaminated water from splashing out
- clean all drain outlets at home once
a day by pouring a teaspoonful of 1:99 diluted household bleach down
each drain outlet - after 5 minutes, rinse with water
- develop a healthy lifestyle - proper
diet, regular exercise, adequate rest and do not smoke
- consult your doctor promptly if you
have a fever (of 38 degrees Celsius or above) or develop symptoms of a
respiratory infection
Extract
from WHO compilation of data on resistance of the SARS Coronavirus against
environmental factors and disinfectants (May 4).
Virus
survival in stool and urine:
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in faeces(and urine) at room temperature for at least 1-2 days
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in stool from diarrhea patients (which has higher pH than normal stool)
for up to 4 days
Virus
survival in cell-culture:
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on plastic surface in room temperature for at least 2 days
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only minimal reduction in virus concentration after 21 days at 4°C and
-80°C
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- avoid sharing eating utensils, and
use proper serving spoons/chopsticks
- avoid eating at buffets where the
food is not covered by a protective cover (many hotel's buffets in
Hong Kong have no such protection)
- the virus is likely to be passed on
from inanimate objects - such as buttons in lifts and building
entrances; door handles; public transport handles; chairs; utensils,;
etc. - so if you need to touch them (and we all do!) wash hands after
and avoid touching your face
- avoid crowded places where close
proximity to others is necessary
- in taxis open your window a little
- PLEASE do not spit - it spreads germs
(and you can also be fined HK$5,000), which others step on and then
carry indoors on their shoes
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WHO Designated Areas with
recent local transmission of Severe Acute Respiratory Syndrome (SARS)
as at 13 June, 2003
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Country
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Area (WHO
recommends postponement of travel to areas marked *)
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Pattern of
local transmission
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Canada
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Toronto
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C |
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China
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Beijing*
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C
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China
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Hong Kong
Special Administrative Region of China
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B
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China
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Taiwan*
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B
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Local transmission has
occurred when one or more reported probable cases of SARS have most likely
acquired their infection locally regardless of the setting in which this
may have occurred. If no new locally acquired cases are identified 20 days
after the last reported locally acquired probable case died or was
appropriately isolated, the area will be removed from this list.
Pattern A
Imported probable SARS case(s) have
produced only one generation of local probable cases, all of whom are
direct personal contacts of the imported case(s).
Pattern B
More than one generation of local
probable SARS cases, but only among persons that have been previously
identified and followed-up as known contacts of probable SARS cases.
Pattern C
Local probable cases occurring among
persons who have not been previously identified as known contacts of
probable SARS cases.
Pattern Uncertain
Insufficient information available
to specify areas or extent of local transmission.
* WHO is currently
recommending, as a measure of precaution, that people planning to travel
to these areas consider postponing all but essential travel.
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